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Gambro Cobe Spectra Essentials Manual
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Introduction2-2 COBE ® Spectra™ Apheresis System • Essentials GuideSpectra System DescriptionThe Spectra system separates and collects blood components fromdonors and patients for cell therapy, therapeutic apheresis, andtransfusion medicine applications. The system collects blood productsfrom donors for transfusion to patients. It can concurrently collectplasma during platelet and WBC collections for use as plasma, freshfrozen plasma, or source plasma for further processing into Factor VIIIand Factor IX concentrates.The Spectra system with software version 5.1 LRS or version 7.0 LRSTurbo collects leukocyte-reduced, extended life platelets for transfusion.The system can estimate platelet yields before a platelet collectionprocedure starts. This enables users to optimize donor pools bycollecting multiple platelet products from donors with sufficiently highplatelet counts and total blood volumes.For patients undergoing therapeutic procedures, the Spectra systemexchanges or depletes blood components. In addition, the systemcollects platelets and plasma from patients for autologous transfusion.The Spectra system with software versions 4.7, 5.1, 6.1, and 7.0processes bone marrow, depletes WBCs, and collects mononuclear cellsand granulocytes (polymorphonuclear cells) from donors or patients.The Spectra system version 6.1 performs automated peripheral bloodstem cell (PBSC) collection, including low volume collection. Thesystem can also concurrently collect plasma with PBSCs for use in cellcryopreservation.The system uses a Dual-Needle (one access needle and one returnneedle) or a Single-Needle (one access/return needle) disposable tubingset to collect platelets. Operators can convert TPE sets from Dual-Needle to Single-Needle, if necessary.The Single-Needle procedure design keeps the extracorporeal volumelow and the process time short. Since the procedure requires onevenipunture for both access and return, it also offers greater comfort fordonors and patients, and is easier for operators to manage.The Spectra system includes the following:• A disposable tubing set, consisting of a separation channel that spinsin the centrifuge to separate blood into its components, and tubingthat routes blood and replacement fluid through the set. See“Disposable Tubing Sets” on page 2-21 for more information.• The COBE Spectra Apheresis System, an automated blood cellseparation device which uses pumps, valves and sensors to controland monitor the extracorporeal circuit during apheresis procedures.The software controls pump flow rates and centrifuge speed toestablish and maintain the RBC/plasma interface. The controlpanel, including the display screen and keyboard, allowscommunication with the Spectra system. The automated systemensures donor/patient safety while allowing operator control.Additional features include quick system set-up, automatic tubingset Prime mode, predictable collection and exchange results,automatic Rinseback mode, and comprehensive troubleshootingdisplay screen messages.Figure 2-1 shows an exterior view of the Spectra system (without aflow path overlay or disposable tubing set installed). |
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